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The inhibitory or enhancing effects of isatuximab and daratumumab on the hydrolase activity of CD38 molecules in MM cells [19, 21, 23, 40] and the potential in vivo impact on ADO production in MM patients remain to be further investigated and clarified [11]

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Reference: AIC100 Aicar 100mg AICAR is an analog of adenosine monophosphate (AMP), a nucleotide that is considered to play an important role in cellular energy metabolism