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10.1111/jpi.12916 75

Piperine Suppresses the Wnt/-Catenin Pathway and Has Anti-cancer Effects on Colorectal Cancer Cells

Arch Intern Med 115:411, 1965

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Superoxide anions (O 2 ), although weak oxidants, ultimately generate highly reactive and harmful species such as hydroxyl radicals (OH) and singlet oxygen ( 1 O 2 ), both of which contribute significantly to oxidative stress (Gulcin et al