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Clinical features and outcomes of complementary and alternative medicine induced acute liver failure and injury

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doi: 10.3390/cells10050971 25 SunJCBeilkeJNLanierLL

Yusuf, M., Khan, M., Khan, R

10 Persistent NF-B activation drives inflammaging, which impairs immune surveillance, reduces T cell diversity, and promotes tissue degeneration

Given the lack of rare missense variants that have been annotated as likely benign or benign in ClinVar, we instead used gnomAD variants (after excluding known or suspected pathogenic variants) as a negative reference set