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The radius of gyration (Rg), the root mean square deviation (RMSD) of the protein backbone and ligand, the minimum distance between the ligand and protein, and the Root Mean Square Fluctuations (RMSF) of residues near the ligand (within 5 Angstroms) were used to analyze these MD trajectories

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p = 8.92e13) (Fig

Potential biomarkers of preeclampsia: inverse correlation between hydrogen peroxide and nitric oxide early in maternal circulation and at term in placenta of women with preeclampsia

Meantime, hepatic and renal function biochemical markers tests exhibited normal ranges of values in the PBS, Gi-F-CAA (8 mg/kg in 100 L PBS), Gi-F-CAA (12 mg/kg in 100 L PBS) and Gi-F-CAA (16 mg/kg in 100 L PBS) treatment groups at 1 day post-injection, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), urea nitrogen (BUN), and creatinine (CRE) levels (Supplementary Fig

10.1038/s41598-024-75476-0 26