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Alimta Dosage and Administration 2.1 Recommended Dosage for Non-Squamous NSCLC The recommended dose of ALIMTA when administered with pembrolizumab and platinum chemotherapy for the initial treatment of metastatic non-squamous NSCLC in patients with a creatinine clearance (calculated by Cockcroft-Gault equation) of 45 mL/min or greater is 500 mg/m2 as an intravenous infusion over 10 minutes administered after pembrolizumab and prior to carboplatin or cisplatin on Day 1 of each 21-day cycle for 4 cycles

Methylation, inflammation, and skin appearance B12 drives the methylation cycle, which among other functions helps regulate homocysteine an amino acid linked to inflammation and vascular stress when it accumulates

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Hi thanks for the reply, I think as I already have Hashimotos and my father and grandmother both had pernicious anaemia, I think a positive diagnosis is more than likely

B12 is stored quite well by the liver, so sometimes we dont see low levels on bloodwork even in someone who might be experiencing low intracellular levels of B12

as this was exploratory there were no study size decisions made a priori