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doi: 10.1152/japplphysiol.00071.2011

Through the regulation of glutamate and GABA, glutamine within the CNS plays an integral role in many aspects of neurobiology and as such disturbances in glutamine metabolism and/or transport have been implicated in a range of pathologies ranging from chronic stress, epilepsy, hepatic encephalopathy, manganese encephalopathy, neurodegenerative disorders and metabolic disease (Reference Huang, Liu and Yin54,Reference Ivens, Caliskan and Papageorgiou55)

Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport

Variants in CD44, CYP3A5, UGT1A9, UGT1A1, UGT2B15 impact risk

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