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The Problem with Conventional Glutathione- Know the Chemistry Glutathione (GSH) is a tripeptide: glutamic acid, cysteine, and glycine

Guzzaloni, G., Grugni, G., Minocci, A., Moro, D

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Structurally, it is the only GPX isoform with a monomeric conformation and a unique catalytic tetrad including Sec, Gln81, Trp136, and Asn137 that enables it to reduce complex hydroperoxides in situ even within membranes (23)

Annu Rev Microbiol 51:7396 Nakamori S, Kobayashi S, Kobayashi C, Takagi H (1998) Overproduction of l-cysteine and l-cystine by Escherichia coli strains with a genetically altered serine acetyltransferase