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Using cannabinoid compounds with no affinity for CB1 receptors from CNS (central nervous system), which drastically limits the selection of effective solutions, or formulating them so that they cannot cross the BBB are two practical ways to avoid the psychotropic action of cannabinoid compounds

Tuma DJ, Thiele GM, Xu D, Klassen LW, Sorrell MF

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Some examples include: Spermicide can be used with barrier methods to further reduce the risk of pregnancy

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