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The CONSORT diagram of the current study is presented in Fig

We found by WB that there was no statistically significant difference between the blank and co-administration groups

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The Work Group members were also concerned about the effect of publication bias on the available medical literature

Genome-wide and targeted DNA methylation analysis identified that the promoter regions of SREBF1 and LDLR, two key regulators of cholesterol biosynthesis, were hypomethylated under vitamin B 12 -deficient conditions, and as a result, their expressions and cholesterol biosynthesis were also significantly increased