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*Correspondence: Hui Zhao [email protected] This article was submitted to Gastroenterology, a section of the journal Frontiers in Medicine ORCID: Na Li orcid.org/0000-0003-2567-3992 Hui Zhao orcid.org/0000-0001-6358-7978 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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One of the hallmark features of RBC senescence is the externalization of phosphatidylserine (PS), which serves as an eat-me signal for macrophage-mediated clearance