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Cagrilintide is in active clinical development

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Some patients report noticing changes within 2-4 weeks, though individual responses vary

The animals were group-housed until one week before treatment initiation, after which they were given daily subcutaneous injections of vehicle or Cagrilintide at doses of 0.3, 3, or 30 nmol/kg for 21 days

Phase 3 TRIUMPH topline figures (often cited around the high-20% range at 6880 weeks) are company-reported and, at the time of writing, are not the peer-reviewed Phase 2 dataset cited above

Correlations between gene modules and experimental conditions (genotype or treatment) were tested using the limma R package, with multiple testing corrections via the BenjaminiHochberg method