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Nrf2 also activates the genes encoding the four major NADPH producing enzymes, G6PD, PGD, ME1, and IDH1, for reducing oxidized glutathione and other cellular components

Its activity is mediated through copper transport, gene modulation, and interaction with extracellular matrix components

Huang S, Yu M, Shi N, et al

Why Astaxanthin Is Different Astaxanthin belongs to a family of compounds called carotenoids, the same group that includes beta-carotene and lutein