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The antiviral activity of bacterial, fungal, and algal polysaccharides as bioactive ingredients: potential uses for enhancing immune systems and preventing viruses

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Schroeder, K

Lactobacillus plantarum L15 alleviates colitis by inhibiting LPS-mediated NF-B activation and ameliorates DSS-induced gut microbiota dysbiosis

All these alterations contribute not only to the weakening of the response to conventional therapy in this population, but also to chronotherapy, which presupposes a physiological rhythmicity that is not observed in these patients, particularly in the presence of comorbidities, polypharmacy, or sleep disorders (Lvi et al., 2010