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injections of vehicle or L2-Cmu (20 mg/kg) once per week and were monitored for interim survival to 24 mo of age ( n = 2438 per group) and sacrificed for blood, tissue, and histopathologic analysis

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Most therapeutic research remains centered around experimental models of disease in rodents with limited work in the larger species, arguably narrowing the utility of these findings in horses on a clinical level

These parameters indicate the maintenance of a more reducing redox environment in Plainsman which may contribute to its better drought tolerance due to the efficient removal of the excess of ROS (Considine and Foyer 2014a)