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Comparative study in Zebrafish and medaka unravels the mechanisms of tissue regeneration

The PI3K-Akt signaling pathway can transmit extracellular stimuli through the cell membrane to the cytoplasm, and plays an important role in testicular development and spermatogenesis 50

Astragaloside IV alleviates neuronal ferroptosis in ischemic stroke by regulating fat mass and obesity-associated-N6-methyladenosine-acyl-CoA synthetase long-chain family member 4 axis

For example, in testicular germ cell tumors, in which TP53 is predominantly wild type, the patients experience better cure rates to a cisplatin-based regimen than most other adult solid tumor patients [38]

Patients usually present with gradual onset of nausea, vomiting, abdominal pain, weight loss and fatigue

Molecular origin of cancer: Catechol estrogen-3,4-quinones as endogenous tumor initiators