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4 Despite its central role in mitochondrial fatty acid oxidation and metabolic homeostasis, the molecular regulation and physiological significance of endogenous carnitine biosynthesis, as well as the identity of the initial transporter that introduces the precursor TML into this pathway, remain incompletely understood

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Senescent but not young RBC, as obtained by density separation, are phagocytosed by macrophages, while phagocytosis of in vitro aged RBC requires opsonization with autologous IgG

At 30 min of ischaemia, the mice were sacrificed by cervical dislocation, and the myocardial area at-risk (ischaemic) and non-risk (control) were quickly issected and snap-frozen in liquid nitrogen

demonstrated through in vivo experiments in mice that the number of osteoclasts decreased, bone resorption decreased, bone mass increased, biomechanical strength was improved, and the occurrence of cancellous femoral bone was reduced in mice that were knocked out or inhibited (106)

Glia 54:214222