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NRF1 binds to palindromic recognition sequences in target gene promoters as a homodimer, functioning as a potent transcriptional activator

Another potential candidate would be the use of oxygenation/oxidizing agents such as chlorine dioxide (ClO 2 ), a gas that is readily dissolved in water and derived from its prodrug sodium chlorite (NaClO 2 ) (Andrs et al., 2022), that has been examined for their ability to penetrate biofilms and to target pathogenic microbes (Behnke and Camper, 2012)

Acknowledgements The author is grateful to the National Institutes of Health (R35GM142882) for support which enables investigations into halogenation biochemistry in the Agarwal laboratory

The cost and availability of auto-antibodies testing, such as intrinsic factor and anti-parietal cell antibodies, can be a barrier to further investigation for vitamin B12 deficiency to exclude pernicious anemia

Qu R, Ji Y, Ling Y, Ye C-Y, Yang S-M, Liu Y-Y, et al