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Experimental observations indicate that AOD 9604 may affect cellular processes such as matrix synthesis and structural integrity in cartilage tissue

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In vivo , they found that NNMT knockdown mice had higher energy expenditures than the control mice with similar body weights [11]

GLUT4, which is primarily located in striated muscle (skeletal and cardiac) and adipose tissue, plays a major role in regulating glucose uptake and overall energy balance