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Spinal surgery to remove the degenerated disc and fuse the adjacent spinal segments may cause degeneration and instability of the neighboring discs (Karppinen et al., 2011)

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[17] [93] However, there remain several challenges to using predictive tools which incorporate genetic variation in clinical practice

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"I don't think we did get the full picture because what, I think, comes out of those emails is that this wasn't a routine thing," Collins said