glutathione peroxidases peroxidase 1 Glutathione Peroxidase (GPx)

10.1016/j.bbagen.2012.10.005 45 MakovecT

These include seven positively regulated cuproptosis genes: ferredoxin1 (FDX1), lipoic acid synthase (LAIS), fatty acid transferase 1 (LIPT1), dihydrolipoicenamide dehydrogenase (DLD), dihydrolipoic acid transacetylase (DLAT), pyruvate dehydrogenase E1-alpha subunit (PDHA1), pyruvate dehydrogenase E1- subunit (PDHB) and three negatively regulated genes: metal-regulated transcription factor 1 (MTF1), glutaminase (GLS), and cell cycle protein-dependent kinase inhibitor 2A (CDKN2A) (see Table 1 below) ( Figure 2 )

In some cases the phenotype is linked to mislocalization of the pigments to the cytoplasm 29 or vesicle-like structures 19,30

2016;113:E456776

The results of Kosmodermas glutathione IV therapy vary from person to person

49th ed