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1 2 Angewandte Chemie International Edition

No metabolites were identified in feces or bile

[6] In the second step, 2,3-bisphosphoglycerate is dephosphorylated into 3-phosphoglycerate

Since this pilot study, a larger group of DOA patients carrying either OPA1 mutations leading to haploinsufficiency or missense point mutations has been treated with idebenone [14]