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In-vitro and endothelial systems Cell-culture assays endothelial tube formation, the chick chorioallantoic membrane assay, OPC differentiation cultures, and neurite-outgrowth assays establish direct molecular actions without the confounds of a whole animal

Due to its phenolic structure, AC directly scavenges reactive oxygen species and activates nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, which upregulates antioxidant enzymes like HO-1 and NQO1, providing cytoprotection against oxidative damage (Wang et al

In each instance the total number of spines was counted for the treatment groups, control, Nle1-AngIV and Dihexa, to ensure an active phenotype

This was not seen in the younger group

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