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Later that year, Ingalls and Warren compared ascorbic acid levels in 20 peptic ulcer patients with 2 healthy hospital workers

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In line with these findings, hypermethylation of the D-loop region was also detected in these patients, which is associated with reduced mtDNA synthesis (91)

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Stress affects the integrity of the mucosal immune system by increasing CD4+ T and CD19+ B cells in the large intestine [18]