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K562 cells were counted and resuspended at 1 10 6 live cells/mL and incubated with 5 M calcein AM for 1 h at 37C with mixing every 10 mins

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Paeoniflorin suppresses neuronal ferroptosis to improve the cognitive behaviors in Alzheimers disease mice

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Among the 38 hits from the screen, we selected the 15 with a stronger senolytic effect on etoposide-treated SK-MEL-103 cells and, taking advantage of inhibitors of apoptosis (emricasan) or ferroptosis (liproxstatin 1), assessed their mode of action (Fig

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10.3233/JAD-2002-4309 J

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