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It is a chemical inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), which catalyzes the methylation of nicotinamide using S-adenosylmethionine as the methyl donor

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study investigator, told BioSpace he has treated a number of patients with Duvyzat who are still ambulatory at 16 or 17 years old, while DMD patients on steroid treatment typically lose the ability to walk around 10 to 13 years of age