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Among the 14 identified candidates, acetylcarnitine was finally selected by confirming whether it was endogenous in the blood, matched with the mass value, and exhibited a significant difference in intensity between the MDD and control groups (Figure 4)

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214,215 A systematic review of 12 clinical trials found that CoQ10 supplementation in patients with CKD significantly reduced blood levels of malonaldehyde, a marker of oxidative stress, and high-sensitivity C-reactive protein (hs-CRP), which is a marker of systemic inflammation

10.1016/j.jphs.2020.07.014 78 LachaierE.LouandreC.GodinC.SaidakZ.BaertM.DioufM.et al (2014)

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