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Stable transduction of quiescent CD34 + CD38 human hematopoietic cells by HIV-1-based lentiviral vectors

demonstrated that adding carnitine orotate complex (900 mg/day, 12 weeks) to metformin therapy significantly augmented ALT reduction versus metformin alone (67)

, Reference Crespo, San-Miguel, Prause, Marroni, Cuevas, Gonzlez-Gallego and Tun2012)

2000 Jul;38(7):625-34 No Abstract [3] Kidd PM

however, individual outcomes may vary

In a study of over 1000 breast cancer patients with diabetes, those taking metformin had an almost 24% lower mortality risk compared with controls, whereas those not taking metformin had an almost 71% higher mortality risk (Hou 2013)