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Although no significant changes in leptin or adiponectin levels have been observed in studies of IF in MS, an observed difference in T-cell subsets in intestines might explain the immunological effects of IF that have been reported in studies (33, 60), which was also a kind of possible therapy for MS (59)

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Table 2 Enzymatic activities and metabolite content in active and dormant M

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These agents can concurrently attenuate the lipid-lowering efficacy of statins and compromise bone mineral density, potentially leading to metabolic disorders and secondary hyperparathyroidism