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Description

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ROS generated by NADPH oxidase affect cell proliferation and differentiation by modulating cell signaling, while excessive suppression of NADPH oxidase may impair its role in maintaining gut barrier stability

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This dysregulation contributes to the loss of tumor suppressor functions, the stabilization of oncogenes, and the modulation of key signaling pathways that promote cancer cell proliferation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 64.He Y.-F., Li B.-Z., Li Z., Liu P., Wang Y., Tang Q., Ding J., Jia Y., Chen Z., Li L., et al

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Moderate age-related decline necessitates more stimulation than younger patients but most retain adequate pituitary reserve for good response

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