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Role of the B helix/BC loop and helices F and G in enzymatic function

Reduced palmitoylation of SQSTM1/p62 in huntington disease is associated with impaired autophagy

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In clinical diagnosis, major plasma protein acts as a useful biomarker of various diseases, including ischemia, cancer, rheumatoid arthritis, severe acute graft-versus-host disease, post-menopausal obesity as well as for conditions that require glycemic control monitoring (Gupta and Lis, 2010)

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