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318 The real-time in vivo bone-sensing smart biomaterials can dynamically adjust treatment protocols based on the actual status of bone tissue, enhance therapeutic outcomes and promotes the swift recovery of bone tissue

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However, restrictions such as a need to proceed efficiently at low protein loadings, solely in aqueous media, and to tolerate potential nonspecific binding to the multitude of possible Lewis-basic residues on protein surfaces, until recently, hindered the use of such reactions for site-specific protein modification

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Clin Kidney J 8:548559