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503 Despite these advances, the use of first- and second-generation mTOR inhibitors has been associated with a range of side effects such as insulin resistance, hyperglycemia, impaired wound healing, hypertension, and various metabolic, renal, and pulmonary complications

Proteomic analysis of LV tissue revealed marked inflammatory and metabolic adaptations in both DM and DM_CKD groups

PD is a chronic progressive disease whose incidence increases with age, and there are currently no fully cured cases

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In a 3-month clinical trial of the drug genistein, patients with PCOS demonstrated a notable reduction in LDL and triglycerides compared with that in the placebo group (47)

CrossRef Original Articles Basic Research Diabetes Promotes Myocardial Fibrosis via AMPK/EZH2/PPAR- Signaling Pathway Shan-Shan Li, Lu Pan, Zhen-Ye Zhang, Meng-Dan Zhou, Xu-Fei Chen, Ling-Ling Qian, Min Dai, Juan Lu, Zhi-Ming Yu, Shipeng Dang, Ru-Xing Wang Diabetes Metab J