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Specifically, under PF conditions, increased ER stress in AEC2 resulted in impaired lipid synthesis, in particular a reduction in unsaturated fatty acid synthesis mediated by stearoyl coenzyme A desaturase 1 (SCD1) Reduced SCD1 activity not only impeded resolution of endoplasmic reticulum stress, but also exacerbated cellular dysfunction, thereby triggering a fibrotic response (Romero et al., 2018a)

& Copeland, W

Jernern F, Elshorbagy AK, Oulhaj A, Smith SM, Refsum H, Smith AD

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Recent results showed that Sedum alfredii associated with 20.5 mgKg 1 of carbendazim-degrading bacterial strains enhanced carbendazim degradation up to 83.3% (Xiao et al., 2013)

Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling