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Conceptually however, EAE presupposes that MS is also driven by a primary autoimmune attack originating in the periphery, and if this assumption proves incorrect, then this model may be fundamentally misleading with respect to the true etiology of MS

Temperature guidelines for powder storage The ideal storage temperatures, ranked from best to acceptable: Freezer storage at -20 degrees Celsius or below is the gold standard

References Sikiric, P., et al

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Its also worth noting that individuals may experience different symptoms or levels of improvement from B12 injections, depending on their health status and B12 levels before injection

The confusion, which is understandable, likely arises from one major overlap: the gut