acyl glutathione what is acyl-glutathione

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Mitochondrial ROS production and oxidative mtDNA damage is increased during reoxygenation in the GPX1 knockout mice, in addition to structural abnormalities in cardiac mitochondria and myocytes, suggesting GPX1 may play an important role in protecting cardiac mitochondria from reoxygenation damage in vivo

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PMID 18450759

discovered a new mitochondrial quality control mode called mitocytosis, in which abnormal mitochondria are released into the extracellular space through migrasomes [73]

So, when we say glutathione is reduced, we mean it can remove oxygen or ROS hence its being an "antioxidant" after which the glutathione becomes oxidized