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Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimers disease pathogenesis

10.3390/antiox12030632 Antioxidants

In contrast, lower dose of LA (25mg/kg) was not found to ameliorate renal dysfunction in our study

Brain Struct Funct 226:24892495

Zileuton, an anti-inflammatory compound, inhibits LOX5 and decreases -secretase, A, and tau after three months of treatment in a 3xTg mouse AD model (Di Meco et al., 2014), demonstrating its broad prospects for clinical use

Sex differences have also been reported: women experience a higher rate of L-DOPA-induced dyskinesia (LID), anxiety and dystonia (San Luciano et al., 2017