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doi: 10.1016/j.redox.2017.05.005 151 WardJZhangSSikoraAMichalskiRYinYD'AlessioAet al

Dietary -mangostin, a xanthone from mangosteen fruit, exacerbates experimental colitis and promotes dysbiosis in mice

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Due to its role as an antioxidant, glutathione is responsible for a variety of vital biological processes: Neutralizes oxidative stress Protects DNA from damage Supports liver detoxification Maintains healthy mitochondrial function Regulates immune system responses Reduces inflammation Assists cellular repair Supports healthy aging and anti-aging processes, helping to reduce the appearance of wrinkles Since a large part of glutathiones role has to do with protecting your cells the building blocks of your body researchers have linked low glutathione levels to everything from accelerated aging to liver disease

Renal proximal tubule cells specifically maintain high intracellular glutathione levels because they are metabolically active and handle a disproportionate share of the body's reabsorption and detoxification work

Kang et al., 2019), and a large mutant collection (Lee et al., 2018)