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The trigeminal nerve pathway, the olfactory nerve pathway, the olfactory mucosal epithelial pathway, and the blood circulation pathway are the primary routes by which drugs enter the brain through the nasal mucosa [94]

Similarly, women with higher adherence to the MeDi exhibited greater abundance of the PTSD-protective bacterium Eubacterium eligens , a short-chain fatty acid producer from dietary fiber, coinciding with lower PTSD severity, indicating that Mediterranean dietary patterns may support gut-mediated neuroprotection (Ke et al., 2023)

Genetic ablation of hepatic Ube2d3 increased hepatic STAT3 phosphorylation and promoted hepatocarcinogenesis in the mice with steatohepatitis induced by CDAA-HFD feeding or liver-specific PTEN deletion

However, the signaling mechanisms promoting BDNF deprivation-induced sensory neuron degeneration are largely unknown

Many athletes make the mistake of either complete inactivity or premature return to normal training, both of which can compromise outcomes

Kim MM, Parmar H, Cao Y, Pramanik P, Schipper M, Hayman J, et al