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Diarrhoea (defined as three or more loose or watery stools per day) is an uncommon side effect of vitamin B12 supplementation , though it is listed as a rare or uncommon adverse reaction in the official product information for both oral cyanocobalamin and injectable hydroxocobalamin preparations

Unlike other vitamins, the absorption of vitamin B12 depends on a protein produced in the stomach called intrinsic factor

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While not always the ideal method of medication administration, inhalants generally cause fewer side effects than those administered via other routes, as serum drug concentrations are typically lower

Biochem Biophys Res Commun (2012) 429(3-4):14855

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