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Description

TGF-1 reduced the expression of p-ERK and downregulated the expressions of Beclin-1, LC3 II/I, and mitochondrial-related apoptotic proteins (Bax/Bcl-2, caspase-9)

At least 1020 % of the general population has been found to progress to NASH and 4055 % of the patients at tertiary care centres have shown the prevalence of NASH ( 13 )

Long-term elevated glucose levels in the body lead to the development of insulin resistance and subsequent hyperinsulinemia, which may lead to increased androgen synthesis by ovarian theca cells