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Sikiric P, Jelovac N, Jelovac-Gjeldum A, Dodig G, Staresinic M, Anic T, et al

For individuals with a single wound focus, local injection provides the most direct delivery

For a 2 mg target dose: Volume to Draw = Desired DoseConcentration = 2 mg5 mg/mL = 0.4 mL Convert to syringe units

or 2 g/kg b.w

By achieving normoglycemia, insulin effectively decreases the accumulation of AGEs and mitigates mitochondrial oxidative stress, consequently alleviating glomerular hyperfiltration and preventing podocyte loss (88)

The number and frequency of injections will depend on the nature of the treatment and can be discussed during your consultation