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ISBN 978-1-4160-2973-1

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Some patients describe a persistent metallic taste, particularly noticeable when eating or drinking, or report that familiar foods taste "off" or different from usual

However, gaps remain in the understanding of subset functions and regulatory mechanisms: in vitro studies rely on limited cell lines (e.g., HD11 macrophages, DF-1 fibroblasts), and the lack of long-term primary immune cell culture systems hinders simulation of in vivo cellular functions in complex microenvironments

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