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Transient cell cycle arrest and arterial differentiation of vein-derived Esm1 + cells Consistent with this and previous studies, the venous EC subclusters in our scRNA-seq analysis predominantly harbor proliferative cells in the G2/M or S phase (Fig

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Specifically, these five GST isozymes could increase the cell viability, reduce the LDH release and ROS accumulation, and facilitate the production of AFBO-GSH, thus alleviating AFB 1 -induced DNA damage in the LMH cells

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While tirzepatide slows gastric emptying and reduces caloric intake through incretin receptor activation, 5-amino-1MQ works intracellularly to inhibit nicotinamide N-methyltransferase (NNMT), shifting cellular metabolism toward fat oxidation independent of appetite suppression