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About this article Cite this article Flanagan, J.L., Simmons, P.A., Vehige, J

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It functions as a cofactor for mitochondrial enzymes specifically pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase that are essential for converting glucose into cellular energy (ATP) [1][2]

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Chronic MR As patients evolve from acute to chronic MR, the LV dilates and changes from a small hyperkinetic chamber in acute MR to a large compliant chamber ( atrial functional MR is less well-studied, and likely related to left atrial enlargement, displacement of posterior annulus onto the crest of the LV, close apposition of posterior mitral leaflet to the LV wall, reduction in posterior leaflet area for coaptation, and counterclockwise torque of the anterior mitral annulus causing tethering of the anterior mitral leaflet with leaflet tenting ( Disease Prognosis and Natural History Severe untreated MR has a fairly poor prognosis irrespective of etiology

Tiene la funcin transportar los cidos grasos hacia el interior de las mitocondrias, las cuales son los orgnulos celulares encargados de aportar la energa necesaria para la actividad celular