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Upon observing mild adverse events, protocols often call for dose reduction, temporary suspension, or discontinuation depending on severity and causality

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Most patients experience fatigue, fevers, and sensitivity to individualized environmental "triggers." Other commonly identified signs and symptoms are as follows: Hot flashes, irregular heartbeat, high or low blood pressure (hypotension and/or hypertension) vertigo, dizziness, forgetfulness, depression or anxiety, headaches, insomnia, restlessness hives or other visible skin rashes arthritis, muscle pain, bone pain, osteoporosis/osteopenia anaphylaxis (a severe allergic reaction) Malabsorption and gastrointestinal distress leading to low iron and low Vitamin D and low Vitamin B12 [2] Diagnosis MCAS can be difficult to diagnose as the cause of the syndrome is still considered to be unknown

It is a chronic inflammatory disorder of the airways in which many immunological cells play a role, including mast cells and eosinophils

Regular alcohol use can "rev up" these enzymes, causing your body to produce even more of the toxic NAPQI byproduct than it normally would

All authors read and approved the final article