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9 Journal of Dental Anesthesia and Pain MedicineReview of BPC-157 pharmacology and reported regenerative effects

and (4) growth hormone receptor upregulation at injury sites, restoring local GHR density without elevating systemic GH levels

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None of the patients had signs of urinary infection, nor were any treated with any oral drugs or intravesical instillations 6 months prior to intravesical injection of BPC-157

Likewise, due to the large presence in human fetuses and adult tissues (in situ hybridization and immunostaining) [14], the concept holds a regulatory physiologic role in bodily functions [14], also based on similar beneficial effects in other species (i.e., birds [73] and insects [74,75,76])