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Nrf2 is expressed the majority of cell types, where it is anchored in the cytosol by an inhibitory protein, Kelch-like ECH-associated protein (Keap1)

D., Flatt, P

10.3390/jcm11144119 J Clin Med

Casuarinin, isolated from SBT leaves, showed inhibitory effects on TNF--induced ICAM-1 expression in human keratinocytes, suggesting its potential as an anti-inflammatory agent (156)