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Allergic reactions like rash, itching, or swelling of the face

Although the results of the study showed to be promising, they acknowledged limitations in the translation of the in vivo studies to clinical trials due to the difference in the human and mouse physiology

Most current studies adopt the classic 16:8 diet (TRE-8) as the TRE intervention pattern, which can emphasize that the eating time needs to be synchronized with the circadian rhythm, allowing subjects to freely ingest energy within an 8-h daily eating window

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doi:10.1016/0165-0173(93)90013-p

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