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Measurement and meaning of cellular thiol: Disufhide redox status

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[PMC free article: PMC2803111] [PubMed: 19644120] 39

(New York, NY: Elsevier) 585603

1.2 Therapeutic uses of Nucleic acid based therapeutics The NBTs as described earlier is used to treat as well as diagnose a variety of CNS disorders, the major ones are briefly discussed below: 1.2.1 Neurodegenerative disorders Parkinsons disease is characterized by progressive loss of dopaminergic neurons leading to movement disorders