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Sikiric, P., Seiwerth, S., Rucman, R., Kolenc, D., Vuletic, L

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the BPC peptide salts of the present invention are useful for the treatment of hypertension, angina, impotence, circulatory shock, septic shock, stroke, inflammation, respiratory distress syndromes, pulmonary hypertension, pancreatitis, adhesion and aggregation of platelets and leukocytes, endothelial dysfunction, and Parkinson's disease

a ) the carboxyl group makes electrostatic interactions with Arg439 and Arg929 of IRAP and b ) phenyl ring of the phenylacetic acid group makes pi-stacking interactions with Tyr961

This is one reason why compounded, clinically supervised formulations are more reliable than DIY preparations

Third, the peptide's effects on growth factor signaling could theoretically interact with fibrotic processes, immunosuppressive therapy, or wound-healing pathways in post-surgical patients